KUSHANDISWA KWEGELATIN MUBIOMEDICAL MATERIALS
Gelatin, yakasikwa biopolymer zvinhu, chikafu chinowedzera chakagadzirirwa neavhareji hydrolysis yemapfupa emhuka, matehwe, tendon, tendon uye zviyero.Hapana chinofananidzwa nemhando iyi yezvigadzirwa zvebiomedical mugelatin, nekuda kweiyo biodegradability, yakanaka biocompatibility, gel uye mutengo wakaderera.Naizvozvo, gelatin yakashandiswa zvakanyanya sechinyakare chemishonga excipient mune biomedical zvinhu.
RopaSubstitutes
Kuwedzerwa ropa kunodiwa muzviitiko zvakawanda, zvakadai sokuvhiyiwa zvishoma kana kubuda ropa kwakanyanya.Nekudaro, kuperevedza kweropa sosi, kurongeka kwakaoma kweropa, uye njodzi yekupihwa kweropa reallogeneic zvinokanganisawo kurongeka, kushanda uye kuchengetedzwa kwekiriniki kurapwa kusvika pamwero mukuru.Iyo nzira yekutsiva plasma inogona kugadzirisa matambudziko aya, saka ine yakakura kiriniki application inogona uye tekinoroji yekuvandudza nzvimbo.Naizvozvo, zvinhu zvegelatin, senge succinyl gelatin uye polygelatin peptide, zvinoshandiswa zvakanyanya sezvinotsiva plasma mukiriniki.Gelatin plasma inotsiva ichashandiswa munjodzi dzakadai sekuderera kweropa uye kuvhunduka.Colloid kupinza kunogona kuwedzera huwandu hweropa uye kuvandudza microcirculation.Gelatin blood substitutes ine zvakawanda zvakanaka, zvakadai sekuderera, kupinza kukuru, kusina chepfu, kusina immunogenicity nezvimwe zvakadaro.
HemostaticMzvinhu
Mumakore achangopfuura, nharaunda yezvokurapa yakabhadhara zvakanyanya kukudziridzwa kwezvinhu zvitsva zvehemostatic.Absorbable gelatin sponge yakwezva kutarisisa nekuti ine zvakanakira hemostatic mhedzisiro, mutengo wakaderera uye yakasimba processability.Iyo hemostatic mechanism yegelatin hemostatic sponge inonyanya kugadzira reticular chimiro nekuvhara tsinga dzeropa, kuitira kuti agglutinate maplatelet uye kuisa fibrinogen.Izvi zvinobatsira zvikuru pakuumbwa kwethrombosis, kuitira kuti kuderedza nguva yekuvhara uye pakupedzisira kumisa kubuda ropa.Zvinoenderana neyayo coagulation maitiro, gelatin hemostatic sponge ine akakosha mabasa emakanika kudzvanya uye kunyudza mvura.Mune iyo yose coagulation process, semuenzaniso, haina kuita basa rakakosha mukusimudzira chizvarwa cheakakosha hemostatic maitiro akadai seprothrombin activation.Iyo yakajairwa inonwisa gelatin sponge inoshandiswa mukiriniki ine zvakawanda zvisingabatsiri, senge kuita kwakakura kwemitumbi yekunze, kuderera kwehemostatic uye kudonha nyore.Parizvino, gelatin inowanzogadziriswa kana kusanganiswa nezvimwe zvinhu kuti ibudise zvinhu zvehemostatic zvine maitiro akanaka.
ZvimweAzvikumbiro
Gelatin inonyanya kubva ku collagen mumatishu emuviri, saka ine yakanakisa biological zvimiro, senge yakanaka biocompatibility uye biodegradability, saka yakashandiswa zvakanyanya mumunda webiomedical.Gelatin inogona kushandiswa kwete chete muzvikamu zviri pamusoro, asiwo mukurapa zvirwere zveganda.Semuenzaniso, gelatin ye hydrolyzed inogona kurapa ganda rakaputika, ichthyosis uye dandruff.Uyezve, gelatin yakashandiswawo zvakanyanya mukurapa kwemukati.MuChinese Pharmacopoeia, inotsanangurwa kuti macromolecular gelatin ine mhedzisiro yekunyorova kuoma uye kuburitsa ropa, uye ine mamwe maitiro ekurapa pazviratidzo zvakawanda seanemia uye kurasikirwa kweropa.Hydrolyzed gelatin inewo maitiro akajeka mukurapa gastritis isingaperi uye zvimwe zviratidzo.
Nguva yekutumira: Aug-11-2021
